Related Experiment Video
Updated: Apr 29, 2026
Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
Determination of visual prognosis in children with open globe injuries
1Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, China.
Insights
Predicting visual outcomes in pediatric open globe injuries is crucial. Factors like younger age, poor initial vision, blunt/missile trauma, and posterior wounds indicate worse outcomes.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Trauma Surgery
Background:
- Open globe injuries in children are a significant cause of vision loss.
- Understanding predictive factors is essential for improving management and outcomes.
Purpose of the Study:
- To identify factors predicting visual outcomes in pediatric open globe injuries.
- To provide guidance for reducing the incidence of these injuries.
Main Methods:
- Retrospective analysis of 140 eyes from 137 pediatric patients treated between 2005-2012.
- Data included demographics, injury characteristics, surgical details, and visual outcomes.
- Follow-up assessed best-corrected visual acuity and complications.
Main Results:
- The study included 137 children (84.7% boys, mean age 11.57 years).
- Common causes included living utensils, industrial tools, and fireworks.
- Sharp force injuries were most frequent (59.1%), followed by missile (24.1%) and blunt (16.8%) injuries.
Conclusions:
- Unfavorable visual outcomes correlate with younger age, poor presenting visual acuity, and blunt/missile injuries.
- Posterior wound location, hyphema, vitreous hemorrhage, and pars plana vitrectomy were also associated with poorer outcomes.
- Findings can inform strategies to prevent and manage pediatric open globe injuries.
Aims:
To determine the predictive factors of visual outcomes in children with open globe injury and to give guidance to reduce the incidence of open globe injury.
Methods:
One hundred and forty eyes of 137 consecutive open globe injury patients, who were treated at the Eye Center of Second Bethune Hospital affiliated with Jilin University between August 2005 and August 2012, were retrospectively analyzed. Data recorded included demographic characteristics, causes of injury, location and extent of injury, presenting visual acuity, detailed ocular anterior and posterior segment evaluations, details of primary and subsequent surgeries, and postoperative complications and outcomes. The follow-up data included the most recent best-corrected visual acuity, complications, and the duration of follow-up.
Results:
Of the 137 patients, there were 116 (84.7%) boys and 21 (15.3%) girls. Their ages ranged between 3 and 17 years old (mean=11.57±4.19 years old). Sixty (43.8%) children had a right eye injury, whereas 74 (54.0%) had a left eye injury. Only three (2.2%) children suffered bilateral eye injury. Living utensils, industrial tools, and fireworks contributed to the most common causes of open globe injury. Eighty-one (59.1%) had sharp force injuries, 23 (16.8%) had blunt injuries, and 33 (24.1%) had missile injuries.
Conclusions:
Unfavorable visual outcomes were related to a younger age at presentation, poor presenting visual acuity, injuries caused by blunt or missile objects, posterior wound location, hyphema, vitreous hemorrhage, and surgical intervention of pars plana vitrectomy.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
01:25Glaucoma: Overview