Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recognizing and managing clinical problems in atopic dermatitis.

J M Hanifin1

  • 1Oregon Health Sciences University Department of Dermatology, Portland 97201.

Allergy Proceedings : the Official Journal of Regional and State Allergy Societies
|November 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pioneers in Dermatology and Venereology: an interview with Jon Hanifin, M.D.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019
Same author

Initial validation of the Burden of Disease in Atopic Eczema instrument, a quality-of-life measure for adult atopic dermatitis.

The British journal of dermatology·2018
Same author

Altered composition of epidermal lipids correlates with Staphylococcus aureus colonization status in atopic dermatitis.

The British journal of dermatology·2017
Same author

What the Eczema Area and Severity Index score tells us about the severity of atopic dermatitis: an interpretability study.

The British journal of dermatology·2015
Same author

Inadequate response to ustekinumab in atopic dermatitis - a report of two patients.

Journal of the European Academy of Dermatology and Venereology : JEADV·2014
Same author

Report from the third international consensus meeting to harmonise core outcome measures for atopic eczema/dermatitis clinical trials (HOME).

The British journal of dermatology·2014

Atopic dermatitis, an inflammatory skin condition, involves immune system defects and overproduction of IgE. Management includes hydration, topical steroids, and trigger avoidance for effective atopic dermatitis treatment.

Area of Science:

  • Immunology
  • Dermatology
  • Allergy

Background:

  • Atopic dermatitis is a common, itchy skin condition linked to a history of allergies.
  • It is characterized by immune system dysregulation, particularly in bone marrow cells.
  • Elevated immunoglobulin E (IgE) levels are a hallmark of the condition.

Purpose of the Study:

  • To outline the key pathophysiological features of atopic dermatitis.
  • To highlight diagnostic and histological findings.
  • To summarize current management strategies for atopic dermatitis.

Main Methods:

  • Review of existing literature on atopic dermatitis.
  • Analysis of clinical and immunological findings.
  • Histopathological examination for characteristic changes like spongiosis.

Related Experiment Videos

Main Results:

  • Primary immune defects in bone marrow cells and IgE overproduction are noted.
  • Abnormalities include vascular, sweating, and itch responses, with some patients showing abnormal methacholine tests.
  • Histology reveals spongiosis, indicative of hypersensitivity reactions.

Conclusions:

  • Atopic dermatitis involves complex immune and physiological abnormalities.
  • Management requires a multifaceted approach including hydration, trigger control, and pharmacotherapy.
  • Awareness of complications like ocular herpes simplex is crucial for comprehensive patient care.