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Updated: Apr 29, 2026

In vitro Organoid Culture of Primary Mouse Colon Tumors
Published on: May 17, 2013
New intracellular and molecular aspects in pathophysiology of colorectal cancer
Payman Ziapour1, Ramin Ataee2, Mohammad Shadifar3
1Cell and Molecular Research Lab, Amol Research Center, Pasteur Institute of Iran, Amol, Iran ; Parasitiology Department, Amol Research Center, Pasteur Institute of Iran, Amol, Iran.
Abstract:
Colorectal cancer is one of the most common malignancy in the world and the second cancer-related death, many molecular and genetic aspects of this disease have been cleared as chromosomal instability and the role of some key proteins as WNT/β catenin, trypsin and others. Also recently the role of folate turnover and some neurotransmitters as serotonin were also considered. The scope of this review is to describe some details about new molecular pathways suggested for occurrence or progress of this disease.
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