Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Biostatistics: Overview01:20

Biostatistics: Overview

1.2K
Biostatistics plays a crucial role in understanding and analyzing data in healthcare and biology. Biostatisticians conduct experiments, gather evidence, and draw meaningful conclusions using statistical methods and techniques. Different variables form the foundation of biostatistical analysis, allowing researchers to understand and interpret data effectively. These variables are classified into different types, each serving a specific purpose in statistical analysis.
Discrete variables are...
1.2K
Overview of Biostatistics in Health Sciences01:19

Overview of Biostatistics in Health Sciences

4.8K
Biostatistics involves the application of statistical techniques to scientific research in health-related fields, including biology and public health. These techniques are essential for designing studies, collecting data, and analyzing it to draw meaningful conclusions. Given the complexity of biological processes, particularly in studies involving human subjects, biostatistical methods are crucial for effectively organizing and interpreting data that might otherwise obscure underlying patterns...
4.8K
Model Approaches for Pharmacokinetic Data: Compartment Models01:14

Model Approaches for Pharmacokinetic Data: Compartment Models

885
Compartmental analysis is a widely adopted approach to characterizing drug pharmacokinetics. It uses compartment models that conceptualize the body as a collection of reversibly communicating compartments, each representing a group of tissues exhibiting similar drug distribution characteristics. The movement rate of the drug between these compartments is typically described by first-order kinetics.
Two primary types of compartment models are recognized: mammillary and catenary. The more...
885
Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches01:14

Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches

727
Drug disposition in the body is a complex process and can be studied using two major approaches: the model and the model-independent approaches.
The model approach uses mathematical models to describe changes in drug concentration over time. Pharmacokinetic models help characterize drug behavior in patients, predict drug concentration in the body fluids, calculate optimum dosage regimens, and evaluate the risk of toxicity. However, ensuring that the model fits the experimental data accurately...
727
Pharmacokinetic Models: Comparison and Selection Criterion01:26

Pharmacokinetic Models: Comparison and Selection Criterion

488
Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.
488
Bioequivalence studies: Biowaivers01:13

Bioequivalence studies: Biowaivers

430
In certain scenarios, in vitro dissolution tests can replace in vivo bioequivalence studies. This is particularly true when a drug product, though available in varying strengths, maintains proportional similarity in its active and inactive ingredients. In such cases, the need for in vivo bioequivalence studies for lower strength variants may be waived, provided dissolution tests and in vivo studies on the highest strength yield satisfactory results.Bioequivalence can be indicated through...
430

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

POT1 and Damage Response Malfunction Trigger Acquisition of Somatic Activating Mutations in the VEGF Pathway in Cardiac Angiosarcomas.

Journal of the American Heart Association·2019
Same author

In vivo phosphoproteomics reveals kinase activity profiles that predict treatment outcome in triple-negative breast cancer.

Nature communications·2018
Same author

Management Control Systems and Clinical Experience of Managers in Public Hospitals.

International journal of environmental research and public health·2018
Same author

Employee reactions to the use of management control systems in hospitals: motivation vs. threat.

Gaceta sanitaria·2017
Same author

Optimizing sharing of hospital biobank samples.

Science translational medicine·2015
Same author

Implementation of a cost-accounting model in a biobank: practical implications.

Pathobiology : journal of immunopathology, molecular and cellular biology·2015

Related Experiment Video

Updated: Apr 29, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
08:01

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

7.3K

Cost model for biobanks.

M Beatriz Gonzalez-Sanchez1, Ernesto Lopez-Valeiras, Manuel M Morente

  • 11 Faculty of Business Administration and Tourism; University of Vigo, Campus of Ourense , Spain .

Biopreservation and Biobanking
|May 20, 2014
PubMed
Summary

This study introduces a cost accounting model for biobanks, essential for assessing the economic viability of biomedical research infrastructures. The model helps analyze costs and value stored biological samples.

Area of Science:

  • Biomedical Research Infrastructure Management
  • Health Economics
  • Biobanking Operations

Background:

  • Increasing budget constraints necessitate economic viability analysis for publicly funded biomedical research infrastructures.
  • Lack of specific cost accounting models for biobanks in scientific literature.
  • Biobanks store diverse human biological samples, complicating cost analysis due to varied processing needs.

Purpose of the Study:

  • To present a foundational cost analysis model applicable to any biobank.
  • To address the need for a standardized cost accounting framework in biobanking.
  • To provide tools for economic evaluation of biobank operations and sample collections.

Main Methods:

  • Identified common basic steps across diverse biobank production processes.

More Related Videos

Creation and Maintenance of a Living Biobank - How We Do It
13:08

Creation and Maintenance of a Living Biobank - How We Do It

Published on: April 10, 2021

8.7K
Establishment of a Clinic-based Biorepository
07:50

Establishment of a Clinic-based Biorepository

Published on: May 29, 2017

6.2K

Related Experiment Videos

Last Updated: Apr 29, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
08:01

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

7.3K
Creation and Maintenance of a Living Biobank - How We Do It
13:08

Creation and Maintenance of a Living Biobank - How We Do It

Published on: April 10, 2021

8.7K
Establishment of a Clinic-based Biorepository
07:50

Establishment of a Clinic-based Biorepository

Published on: May 29, 2017

6.2K
  • Developed a cost model based on six stages and four cost objects derived from the Spanish National Biobank Network.
  • Provided templates and examples for cost identification and classification within biobanks.
  • Main Results:

    • The proposed model enables detailed cost analysis for each stage of biobank sample production.
    • Facilitates accurate cost object identification and classification.
    • Offers a methodology for assigning economic value to stored biological samples.

    Conclusions:

    • The cost analysis model provides crucial economic insights for biobank management.
    • Enables evaluation of production process efficiency and financial viability of sample collections.
    • Supports informed decision-making in resource allocation for biomedical research infrastructures.