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Published on: November 11, 2025
Idiopathic lymphoplasmacellular mucositis-dermatitis of the eyelid
Seema R Gupta1, Eric A Steele, Alvin R Solomon
1*Department of Ophthalmology, Casey Eye Institute at Oregon Health & Science University; †Operative Care Division, Portland Veterans Affairs Medical Center; and ‡Departments of Dermatology and Pathology, Oregon Health & Science University, Portland, Oregon, U.S.A.
Abstract:
Idiopathic lymphoplasmacellular mucositis-dermatitis is a rare mucosal or cutaneous disorder characterized clinically by papules or plaques with variable erosion and microscopically by dense dermal inflammatory cell infiltrates with numerous plasma cells. It has been described in the oral and upper aerodigestive tracts, male and female genitalia, and other mucosal surfaces. In this article, the authors describe a case of idiopathic lymphoplasmacellular mucositis-dermatitis occurring in the skin of the eyelid that was removed by excisional biopsy and has not recurred in the 19-month follow-up period.
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