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Canine low-grade intra-orbital myxosarcoma: case report
Cecília B Campos1, Fernanda C Nunes, Conrado O Gamba
1Laboratory of Comparative Pathology, Department of General Pathology, Biological Science Institute, Federal University of Minas Gerais (UFMG), Belo Horizonte, MG, 31270-901, Brazil.
Veterinary Ophthalmology
|May 20, 2014
Summary
This study details a rare canine intra-orbital low-grade myxosarcoma, characterized by specific histological features. Surgical excision resulted in a complete recovery, indicating a favorable prognosis for this tumor type.
Area of Science:
- Veterinary Pathology
- Oncology
Background:
- Intra-orbital tumors in canines are uncommon.
- Accurate diagnosis and prognosis are crucial for effective treatment.
Observation:
- A canine patient presented with a two-year history of a neoplastic mass behind the right eye.
- The mass exhibited mesenchymal spindle and stellate cell proliferation with a myxoid matrix.
Findings:
- Histopathological analysis revealed a low-grade myxosarcoma with moderate anisokaryosis and a low mitotic index.
- Immunohistochemical staining was positive for vimentin and moderately positive for periodic acid-Schiff (PAS).
- The tumor was negative for Gomori trichrome and alpha-smooth muscle actin (α-SMA).
Implications:
- This case highlights the importance of comprehensive histopathological and immunohistochemical evaluation for diagnosing canine intra-orbital low-grade myxosarcoma.
- Surgical excision led to a disease-free outcome one year post-surgery, suggesting a good prognosis with appropriate intervention.
