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Related Concept Videos

Conditioned Taste Aversion01:14

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Conditioned taste aversion, also known as sauce béarnaise syndrome, is a phenomenon in which an individual develops an aversion to a certain food taste following a negative experience, typically illness. This form of aversion is a type of classical conditioning in which the taste of the food (conditioned stimulus, CS) is associated with the experience of illness (unconditioned stimulus, UCS).
A notable characteristic of conditioned taste aversion is that it often requires only a single...
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Related Experiment Video

Updated: Apr 29, 2026

Assessment of Social Transmission of Food Preferences Behaviors
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Rat strains with different metabolic statuses differ in food olfactory-driven behavior.

Karine Badonnel1, Marie-Christine Lacroix1, Didier Durieux1

  • 1INRA, UR1197, Neurobiologie de l'Olfaction, 78350 Jouy-en-Josas, France.

Behavioural Brain Research
|May 20, 2014
PubMed
Summary

Metabolic status significantly impacts how animals perceive food odors and find food. Obesity alters gene expression in the olfactory system, affecting food-driven behaviors.

Keywords:
FastingLou/CObesityOlfactionSniffingZucker

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Area of Science:

  • Neuroscience
  • Metabolic Research
  • Olfactory System Function

Background:

  • Food intake is regulated by olfactory cues and metabolic state.
  • Energy balance hormones like insulin and leptin influence olfactory function and feeding behaviors.

Purpose of the Study:

  • To investigate how endocrine system modulation affects the olfactory system.
  • To examine the impact of metabolic status on food-odor driven behaviors in different rat strains.

Main Methods:

  • Compared four rat strains (obese Zucker, obesity-resistant Lou/C, and counterparts) differing in energy status and hormone levels.
  • Assessed metabolic parameters, food-odor driven behaviors (activity, sniffing time), and food reward localization in fed and fasted states.
  • Analyzed gene expression profiles of leptin, insulin, orexin, and their receptors in the hypothalamus and olfactory system.

Main Results:

  • Obese rats showed high interest in food odor, unaffected by fasting, unlike lean rats.
  • Fasting improved food search performance in Lou/C rats, while other strains improved over time.
  • Metabolic and behavioral changes correlated with altered gene expression in the hypothalamus and olfactory pathways.

Conclusions:

  • Obesity is associated with changes in olfactory pathway gene expression, influencing food odor-driven behaviors.
  • Long-term metabolic status significantly affects food-olfactory driven behaviors.