First experiences with clinical application of cultured auto-epithelium grafts

A modified method of in vitro cultivation of human keratinocytes was used to grow epidermal grafts. Grafts were applied to four patients, onto different types of wound: xenograft pretreated wounds, fresh donor sites, granulating wounds, and allogenic dermis left in place after removal of allogenic epidermis at the stage of starting rejection. Except for hypertropic granulating wounds in one patient all the other applications were successful.