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Related Experiment Video

Updated: Apr 29, 2026

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Self-expanding prostheses for transcatheter aortic valve replacement.

Robert Kumar1, Azeem Latib2, Antonio Colombo2

  • 1Division of Cardiology, Sharp Rees-Stealy Medical Group, San Diego, CA.

Progress in Cardiovascular Diseases
|May 20, 2014
PubMed
Summary

Transcatheter aortic valve replacement (TAVR) offers a safe alternative for high-risk patients. This review examines self-expanding transcatheter heart valves (THVs), highlighting design differences and the need for comparative studies.

Keywords:
Aortic stenosisAortic valvePercutaneousSelf-expandingTranscatheter

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Area of Science:

  • Cardiology
  • Medical Devices
  • Interventional Cardiology

Background:

  • Transcatheter aortic valve replacement (TAVR) is a key alternative to surgical aortic valve replacement for high-risk and inoperable patients.
  • Established safety and efficacy of TAVR are supported by clinical trials and registry data.
  • Patient selection for TAVR often considers advanced age and significant comorbidities.

Purpose of the Study:

  • To review various designs of self-expanding transcatheter heart valves (THVs).
  • To discuss the potential advantages of different THV designs in deployment and complication reduction.
  • To highlight THVs that are currently available or have been successfully implanted in humans.

Main Methods:

  • Literature review of self-expanding transcatheter heart valve (THV) designs.
  • Analysis of available data on THV implantation and early outcomes.
  • Comparison of different THV designs based on available evidence.

Main Results:

  • Multiple self-expanding transcatheter heart valve (THV) designs are available or have undergone human implantation.
  • Early results for new THV designs show promise.
  • Valve design variations may influence deployment accuracy and complication rates.

Conclusions:

  • Self-expanding THVs represent an evolving area in TAVR.
  • Differences in THV design may lead to distinct clinical advantages.
  • Further comparative studies are necessary to determine the relative performance of these devices.