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[Decrease in the serum concentration of triiodothyronine in patients with acute edematous pancreatitis].

R Medina-Santillán, J A Vázquez-Savedra, M Tanimoto

    Archivos De Investigacion Medica
    |July 1, 1989
    PubMed
    Summary

    Acute pancreatitis can cause a temporary decrease in triiodothyronine (T3) levels, mimicking hypothyroidism. Thyroxine (T4) and TSH levels remained normal in patients with severe pancreatitis.

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    Clinical radiology·2016

    Area of Science:

    • Endocrinology
    • Gastroenterology
    • Internal Medicine

    Context:

    • Acute edematous pancreatitis is a critical condition requiring emergency hospitalization.
    • Thyroid hormone levels are crucial indicators of metabolic status.
    • Assessing thyroid function during acute illness is important for patient management.

    Purpose:

    • To investigate the impact of acute edematous pancreatitis on thyroid hormone profiles (T3, T4, TSH).
    • To determine if pancreatitis affects thyroid function and potentially leads to subclinical hypothyroidism.

    Summary:

    • Serum concentrations of triiodothyronine (T3), Thyroxine (T4), and Thyrotropine (TSH) were measured in ten patients with acute edematous pancreatitis.
    • Results showed a significant decrease in T3 levels 72 hours post-admission, while T4 and TSH remained within normal ranges.

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  • This T3 reduction suggested a state of transient hypothyroidism, unassociated with clinical signs.

    • Impact:

    • Highlights a potential biochemical alteration in thyroid function during acute pancreatitis.
    • Suggests that decreased T3 may be a transient response to severe illness rather than indicative of true thyroid disease.
    • Informs clinical interpretation of thyroid function tests in patients with acute pancreatitis.