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Liposarcoma of the great toe: a case report
Jessica Daniels1, Carl Green2, Ashok Paul3
1Medical Student, University of Manchester, Manchester, United Kingdom.
Summary
This case study details a rare pleomorphic liposarcoma of the great toe, a type of soft tissue sarcoma. Prompt diagnosis and treatment led to a good functional outcome for the patient.
Area of Science:
- Oncology
- Orthopedic Surgery
- Radiology
Background:
- Soft tissue sarcomas are rare, with liposarcomas being the most common subtype.
- Pleomorphic liposarcoma, a high-grade variant, typically affects the thigh and accounts for 5% of liposarcoma diagnoses.
Observation:
- A 57-year-old female presented with a 5-year history of a painless swelling on her left great toe, initially misdiagnosed as an ingrown toenail.
- Magnetic resonance imaging (MRI) and core biopsy confirmed a diagnosis of grade 2 pleomorphic liposarcoma.
Findings:
- The patient underwent neoadjuvant radiotherapy followed by amputation of the great toe and proximal first metatarsal.
- One-year follow-up showed no evidence of local recurrence or metastatic disease.
- The patient achieved a good functional outcome with prosthesis use.
Implications:
- This represents the first documented case of high-grade pleomorphic liposarcoma occurring in the great toe.
- Highlights the importance of a high index of suspicion for soft tissue masses to ensure timely diagnosis and treatment of potentially fatal sarcomas.
