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Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
Traumatic brain injury: considering collaborative strategies for early detection and interventional research
Cherise Charleswell1, Brian Ross1, Thao Tran1
1Department of Magnetic Resonance Imaging, Huntington Medical Research Institutes, Pasadena, California, USA.
Abstract:
Mild traumatic brain injury (mTBI) is a graded sequence of injuries, which is clinically defined based on subjective symptoms observed by clinicians and/or those reported by patients. Much of the focus on research and prevention of mTBI has been on professional or collegiate-level athletes, despite children and young teenagers being at greatest risk for mTBI. Further, continued involvement in sports across the lifespan, increases the likelihood that youth athletes may sustain repetitive brain trauma, which may result in permanent neurological and psychological deficits. Thus, there is a clear need for a population health initiative and research efforts that focus on the juvenile athlete population; in order to fill in the gap in knowledge about the long-term physiological effects of injury and social outcomes, as well as devise strategies that can help in early detection, prevention and treatment; and in the setting of evidence-based Return-To-Play guidelines.

