Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cerebral Hemispheres

Cerebral Hemispheres

The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...

Cerebrum: Anatomical Overview II

Cerebrum: Anatomical Overview II

Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...

Lateralization

Lateralization

Brain lateralization refers to the division of mental processes and functions between the two hemispheres of the brain, a phenomenon that optimizes neural efficiency and underpins complex abilities in humans. This specialization allows each hemisphere to perform tasks where it has a comparative advantage, facilitating more refined cognitive capabilities across different domains.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Phenotypic characteristics of paroxysmal dyskinesia in 25 cats.

The Journal of small animal practice·2026

Same author

Parents/caregivers' perceptions of the influence of oral health on the quality of life of paediatric patients with autism spectrum disorder.

European journal of paediatric dentistry·2026

Same author

Parental-caregivers perceptions questionnaire (P-CPQ): linguistic validation of the Italian version of the questionnaire.

European journal of paediatric dentistry·2026

Same author

WEARnCARE, a decision support system to enhance monitoring of motor performance in Parkinson's disease patient's journey<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2025

Same author

Primary intracranial meningeal histiocytic sarcoma causing calvarial hyperostosis in a dog.

The Journal of small animal practice·2025

Same author

Analysis of sleep and symptoms related to OSAS in a group of paediatric patients with Down syndrome.

European journal of paediatric dentistry·2023

Same journal

Dietary-responsive disseminated eosinophilia in a border terrier.

Journal of veterinary internal medicine·2026

Same journal

Clinical features, diagnostic findings, and outcomes of emphysematous cholecystitis in 35 dogs: a retrospective case series.

Journal of veterinary internal medicine·2026

Same journal

Characterization and outcomes of cats with cardiomyopathy undergoing subcutaneous ureteral bypass device placement.

Journal of veterinary internal medicine·2026

Same journal

Multisite sampling improves consensus cytologic interpretation in bone marrow evaluation of dogs.

Journal of veterinary internal medicine·2026

Same journal

Efficacy and safety of canagliflozin in insulin dysregulated horses: a 4-week multi-arm, double-blind, randomized, clinical trial.

Journal of veterinary internal medicine·2026

Same journal

Use of C-peptide and homeostasis model assessment of insulin resistance to assess insulin resistance in dogs.

Journal of veterinary internal medicine·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 29, 2026

Exploring Deep Space - Uncovering the Anatomy of Periventricular Structures to Reveal the Lateral Ventricles of the Human Brain

Exploring Deep Space - Uncovering the Anatomy of Periventricular Structures to Reveal the Lateral Ventricles of the Human Brain

Published on: October 22, 2017

Corpus callosal abnormalities in dogs.

R Gonçalves¹, H Volk, P M Smith

¹Department of Veterinary Science, Small Animal Teaching Hospital, University of Liverpool, Neston, UK.

Journal of Veterinary Internal Medicine

|May 21, 2014

Summary

This summary is machine-generated.

Corpus callosal abnormalities (CCA) in dogs are rare and poorly understood. This study details their clinical signs and MRI findings, revealing common neurological and thirst regulation issues, often linked to holoprosencephaly.

Keywords:

Adipsia Corpus callosum Dog Holoprosencephaly

More Related Videos

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions

Published on: February 15, 2021

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

Related Experiment Videos

Last Updated: Apr 29, 2026

Exploring Deep Space - Uncovering the Anatomy of Periventricular Structures to Reveal the Lateral Ventricles of the Human Brain

Exploring Deep Space - Uncovering the Anatomy of Periventricular Structures to Reveal the Lateral Ventricles of the Human Brain

Published on: October 22, 2017

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions

Published on: February 15, 2021

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE

Published on: August 16, 2024

Area of Science:

Veterinary Neurology
Comparative Neuroanatomy
Canine Genetics

Background:

Corpus callosal abnormalities (CCA) in dogs are infrequently documented and lack detailed characterization.
Understanding CCA is crucial for diagnosing neurological disorders in canines.

Purpose of the Study:

To characterize the clinical presentation and magnetic resonance imaging (MRI) findings in dogs diagnosed with CCA.
To provide a comprehensive overview of this rare condition in veterinary medicine.

Main Methods:

A retrospective analysis of 15 client-owned dogs diagnosed with corpus callosum malformations.
Exclusion of cases where CCA was considered secondary to other conditions.
Review of clinical records and MRI scans for detailed assessment.

Main Results:

Staffordshire Bull Terriers and Miniature Schnauzers were the most affected breeds.
Common clinical signs included adipsia/hypodipsia with hypernatremia, tremors, and seizures.
MRI revealed varying degrees of corpus callosum malformation, with rostral absence and caudal hypoplasia being most frequent. Lobar holoprosencephaly was observed in 14 dogs.

Conclusions:

While adipsia is often associated with CCA, 12 of 15 dogs presented with this sign.
The rostral portion of the corpus callosum is most commonly and severely affected.
Fusion of midline structures rostral to the corpus callosum, potentially impacting thirst regulation, was noted in most cases.