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Updated: Apr 29, 2026

NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose
Published on: December 30, 2025
Non-enzymatic glucose sensors based on controllable nanoporous gold/copper oxide nanohybrids
Xinxin Xiao1, Meng'en Wang1, Hui Li1
1Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials, Ministry of Education, School of Materials Science and Engineering, Shandong University, Jinan 250061, People׳s Republic of China.
Abstract:
A kind of dealloyed nanoporous gold (NPG)/ultrathin CuO film nanohybrid for non-enzymatic glucose sensing has been prepared by a simple, in-situ, time-saving and controllable two-step electrodeposition. The three-dimensional and bicontinuous nanoporous structure of the nanocomposites have been characterized by scanning electron microscope (SEM) and transmission electron microscopy (TEM), and the electrochemical tests have been estimated by cyclic voltammetry and single potential step chronoamperometry (SPSC). The optimal NPG/CuO electrode exhibits great electrocatalytic activity towards glucose oxidation and also shows obvious linear response to glucose up to 12 mM with a high sensitivity of 374.0 µA cm(-2)mM(-1) and a good detection limit of 2.8 µM (S/N=3), as well as strong tolerance against chloride poisoning and interference of ascorbic acid and uric acid.

