Related Experiment Video
Updated: Apr 29, 2026

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
Published on: December 11, 2016
Creatine supplementation prevents acute strength loss induced by concurrent exercise
Vítor de Salles Painelli1, Victor Tavares Alves, Carlos Ugrinowitsch
1School of Physical Education and Sport, University of Sao Paulo, Av Prof. Mello Moraes, 65-Butantã, São Paulo, SP, 05508-030, Brazil.
Creatine supplementation helps maintain strength endurance during concurrent aerobic and strength training. This suggests creatine can counteract the negative effects of combining different exercise types on performance.
Area of Science:
- Exercise Physiology
- Sports Nutrition
- Human Performance
Background:
- Concurrent exercise, combining aerobic and strength training, can lead to interference effects, potentially impairing performance in one or both modalities.
- Creatine supplementation is widely used to enhance high-intensity exercise performance, but its role in mitigating concurrent training interference is less understood.
Purpose of the Study:
- To investigate the impact of creatine supplementation on the acute interference of aerobic exercise on subsequent dynamic strength and strength endurance.
- To determine if creatine can mitigate performance decrements when strength training follows aerobic exercise.
Main Methods:
- Thirty-two recreationally strength-trained men participated in a study involving graded exercise tests and baseline strength assessments.
- Participants were randomized into creatine (CR) or placebo (PL) groups, receiving supplementation for 7 days followed by maintenance doses.
- Experimental sessions involved treadmill running (continuous or intermittent) followed by leg-press or bench-press strength endurance (SE) and one-repetition maximum (1RM) tests.
Main Results:
- Creatine supplementation maintained leg-press strength endurance after intermittent aerobic exercise, unlike the placebo group which showed a significant decrease.
- Bench-press strength endurance was significantly enhanced by creatine supplementation following both continuous and intermittent aerobic exercise.
- While creatine showed minor increases in 1RM, the placebo group only maintained their 1RM, indicating a potential benefit of creatine for maximal strength preservation.
Conclusions:
- Creatine supplementation may counteract the acute interference effect on strength performance commonly observed in concurrent exercise protocols.
- This finding suggests creatine can be a beneficial ergogenic aid for individuals engaging in combined aerobic and strength training regimens.
More Related Videos
07:40Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training
Published on: October 10, 2019
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
Related Concept Videos
Muscle Recovery and Fatigue
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Exercise and Muscle Performance
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Energy Supply for Muscle Contraction
Skeletal Muscle Relaxants: Adverse Effects
Unlike...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...