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Related Concept Videos

Hypodermis01:02

Hypodermis

7.7K
The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
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Papillary Dermis01:11

Papillary Dermis

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
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Loose Connective Tissue01:26

Loose Connective Tissue

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Loose connective tissue is found between many organs. Its main function is to absorb shock and bind tissues together. It also allows water, salts, and various nutrients to diffuse into cells that are embedded in it or present in adjacent tissues.
Adipose Tissue
Adipose tissue consists primarily of fat storage cells called adipocytes and little extracellular matrix. A large number of capillaries present within adipose tissue allow rapid mobilization of lipid molecules. White adipose tissue is...
8.0K
Reticular Dermis01:15

Reticular Dermis

4.6K
The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
4.6K
Layers of Connective Tissue Proper01:21

Layers of Connective Tissue Proper

8.0K
Fascia, a thin layer of fibrous connective tissue, is distributed throughout the body. It demarcates and forms a supportive covering over skeletal muscles, bones, blood vessels, and organs. There are three main types of facia— superficial fascia, deep fascia, and subserous fascia. These are all present at different depths in the body. Fascia reduces the friction and permits muscles, joints, and organs to easily slide against each other, facilitating movement of the body and preventing...
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Related Experiment Video

Updated: Apr 29, 2026

Identification and Dissection of Diverse Mouse Adipose Depots
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Identification and Dissection of Diverse Mouse Adipose Depots

Published on: July 11, 2019

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Defining dermal adipose tissue.

Ryan R Driskell1, Colin A B Jahoda, Cheng-Ming Chuong

  • 1Centre for Stem Cells and Regenerative Medicine, King's College London, Great Maze Pond, London, UK.

Experimental Dermatology
|May 21, 2014
PubMed
Summary
This summary is machine-generated.

Researchers propose new terms for skin fat: intradermal adipocytes and dermal white adipose tissue. This clarifies their distinct development and role in skin health, separate from subcutaneous fat.

Keywords:
adipocytesdermal adipose tissuedermisintradermalskin

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Identification and Dissection of Diverse Mouse Adipose Depots
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Localization, Identification, and Excision of Murine Adipose Depots
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Area of Science:

  • Dermatology
  • Adipose Tissue Biology
  • Developmental Biology

Background:

  • Adipose tissue is closely associated with the skin across many species.
  • Historically, this skin-associated adipose tissue has been referred to by various terms, including subcutaneous adipose, hypodermis, and subcutis.
  • Recent findings suggest a distinct developmental origin for skin adipocytes compared to subcutaneous adipose tissue.

Purpose of the Study:

  • To explore the evolution and development of skin-associated adipose tissue.
  • To establish a clear nomenclature for this distinct adipose tissue layer.
  • To differentiate skin adipocytes from subcutaneous adipose tissue based on developmental origins and function.

Main Methods:

  • Review of existing literature on skin and adipose tissue development.
  • Analysis of developmental pathways for dermal fibroblasts and adipocytes.
  • Comparison of adipocyte development in skin versus subcutaneous depots.

Main Results:

  • Skin adipocytes share a common precursor with dermal fibroblasts during development.
  • The development of intradermal adipocytes is independent of subcutaneous adipose tissue development.
  • Skin adipocytes play a role in epidermal homeostasis, hair follicle regeneration, and wound healing.

Conclusions:

  • Propose the nomenclature 'intradermal adipocytes' for the cells and 'dermal white adipose tissue' for the adipose layer beneath the reticular dermis.
  • This refined nomenclature distinguishes skin adipocytes from subcutaneous adipose tissue.
  • Clarifies the unique developmental origins and functional significance of dermal white adipose tissue.