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Antibiotics from myxobacteria
Till F Schäberle1, Friederike Lohr, Alexander Schmitz
1Institute for Pharmaceutical Biology, University of Bonn, Nussallee 6, 53115 Bonn, Germany. till.schaeberle@uni-bonn.de g.koenig@uni-bonn.de.
Natural Product Reports
|May 21, 2014
Abstract:
Covering: up to the end of 2013. Myxobacteria produce a vast range of structurally diverse natural products with prominent biological activities. Here, we provide a detailed description and judge the potential of all antibiotically active myxobacterial compounds as lead structures, pointing out their particularities and, if known, their mode of action. Thus, the review provides an overview of the potential of specific compounds, suitable for future investigations and possible clinical applications.