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Laboratory Scale Production and Purification of a Therapeutic Antibody
09:54

Laboratory Scale Production and Purification of a Therapeutic Antibody

Published on: January 24, 2017

MAbImprove: a French "Laboratoire d'excellence" (LabEx) dedicated to therapeutic antibodies

André Pèlegrin1, Arnaud Daguet2, Hervé Watier3

  • 1IRCM; Institut de Recherche en Cancérologie de Montpellier; INSERM, U896; Université Montpellier; Institut régional du Cancer Montpellier; Montpellier, France.

Mabs
|May 21, 2014
PubMed
Abstract

No abstract available in PubMed .

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Hybridoma Technology01:31

Hybridoma Technology

Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation, polyethylene glycol...

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