The end or the start of understanding the genetics of type 2 diabetes

Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed.

Science (New York, N.Y.)·2026

Risk of major adverse cardiovascular events and all-cause mortality in type 2 diabetic patients receiving insulin versus non-insulin treatment intensification.

Scientific reports·2025

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.

medRxiv : the preprint server for health sciences·2025

Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.

Nature communications·2025

Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity.

EMBO molecular medicine·2025

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.

Nature·2024

The cholesterol, high-density lipoprotein, and glucose index and its derivatives related to obesity and inflammation as novel metabolic markers for predicting new-onset cardiovascular-liver-metabolic multimorbidity: A prospective cohort study.

Journal of diabetes investigation·2026

Diabetes attenuates weight reduction-mediated liver fibrosis regression in persons with morbid obesity.

Journal of diabetes investigation·2026

A study of changes in insulin requirements related to the menstrual cycle in Japanese women with type 1 diabetes using the advanced hybrid closed-loop system.

Journal of diabetes investigation·2026

LGR6 couples maresin 1 signaling to glycolytic flux and protein lactylation for the rescue of diabetic cardiomyopathy.

Journal of diabetes investigation·2026

Fasting proinsulin as a predictor of future glucose tolerance deterioration in Japanese adults.

Journal of diabetes investigation·2026

Renal glycogen handling in diabetes: A narrative review of diabetic kidney disease pathogenesis.

Journal of diabetes investigation·2026

Permanent congenital hypothyroidism with GBP1 p.Leu187Pro: clinical follow-up data and epigenetic insights.

Journal of pediatric endocrinology & metabolism : JPEM·2026

Association of HbA1c with Time in Range, Time in Tight Range, Empirically Derived Continuous Glucose Monitoring Glucose Ranges, and Mean Glucose.

Diabetes technology & therapeutics·2026

Integrative genomic and functional analysis identifies BCL10 as a novel driver of trophoblast senescence in preeclampsia.

Journal of hypertension·2026

The mutational and clinical spectrum of EYS-associated retinitis pigmentosa in an Eastern European and Northern Asian cohort: two recurrent founder alleles.

Frontiers in genetics·2026

The role of methylation and structural variants in shaping the recombination landscape of barley.

The Plant journal : for cell and molecular biology·2026

How to write (and review) a Genome Report.

Genome biology and evolution·2026

Related Experiment Videos

The end or the start of understanding the genetics of type 2 diabetes

Related Concept Videos

Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed.

Risk of major adverse cardiovascular events and all-cause mortality in type 2 diabetic patients receiving insulin versus non-insulin treatment intensification.

Multi-ancestry polygenic risk scores for the prediction of type 2 diabetes and complications in diverse ancestries.

Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.

Identification of PTGR2 inhibitors as a new therapeutic strategy for diabetes and obesity.

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology.

The cholesterol, high-density lipoprotein, and glucose index and its derivatives related to obesity and inflammation as novel metabolic markers for predicting new-onset cardiovascular-liver-metabolic multimorbidity: A prospective cohort study.

Diabetes attenuates weight reduction-mediated liver fibrosis regression in persons with morbid obesity.

A study of changes in insulin requirements related to the menstrual cycle in Japanese women with type 1 diabetes using the advanced hybrid closed-loop system.

LGR6 couples maresin 1 signaling to glycolytic flux and protein lactylation for the rescue of diabetic cardiomyopathy.

Fasting proinsulin as a predictor of future glucose tolerance deterioration in Japanese adults.

Renal glycogen handling in diabetes: A narrative review of diabetic kidney disease pathogenesis.

Permanent congenital hypothyroidism with GBP1 p.Leu187Pro: clinical follow-up data and epigenetic insights.

Association of HbA1c with Time in Range, Time in Tight Range, Empirically Derived Continuous Glucose Monitoring Glucose Ranges, and Mean Glucose.

Integrative genomic and functional analysis identifies BCL10 as a novel driver of trophoblast senescence in preeclampsia.

The mutational and clinical spectrum of EYS-associated retinitis pigmentosa in an Eastern European and Northern Asian cohort: two recurrent founder alleles.

The role of methylation and structural variants in shaping the recombination landscape of barley.

How to write (and review) a Genome Report.

Related Experiment Videos

The end or the start of understanding the genetics of type 2 diabetes

Related Concept Videos

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