Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tail-anchoring of Proteins in the ER Membrane01:45

Tail-anchoring of Proteins in the ER Membrane

2.8K
Tail-anchored, or TA, proteins are estimated to make up to 3-5% of membrane proteins found in the eukaryotic cell. Such proteins have a single transmembrane domain located approximately 30 amino acid residues upstream from the C-terminal end. As a result, the signal recognition particle (SRP) cannot guide a TA protein to the ER membrane for cotranslational insertion. Hence, they are integrated into the ER membrane post-translationally using their C-terminal end as the anchor. TA proteins...
2.8K
Protein Modifications in the RER01:26

Protein Modifications in the RER

5.6K
Modification of secretory and transmembrane proteins entering the rough ER begins in the ER lumen. These modifications aid in protein folding and stabilize the acquired tertiary structure. Protein modifications in the rough ER co-occur at different stages of protein folding.
Broadly, these modifications can be categorized into four main categories — glycosylation, formation of disulfide bonds, assembly of protein subunits, and specific proteolytic cleavages like removal of signal...
5.6K
Allosteric Proteins-ATCase01:19

Allosteric Proteins-ATCase

4.8K
Binding sites linkages can regulate a protein's function.  For example, enzyme activity is often regulated through a feedback mechanism where the end product of the biochemical process serves as an inhibitor.
Aspartate transcarbamoylase (ATCase) is a cytosolic enzyme that catalyzes the condensation of L-aspartate and carbamoyl phosphate to  N-carbamoyl-L-aspartate. This reaction is the first step in pyrimidine biosynthesis. UTP and CTP, the end products of the pyrimidine synthesis...
4.8K
Sulfur Assimilation01:20

Sulfur Assimilation

553
Sulfur is an essential element in biological systems, contributing to synthesizing key biomolecules, including amino acids such as cysteine and methionine, and cofactors such as coenzyme A and biotin. Microorganisms primarily assimilate sulfur as sulfate (SO₄²⁻) from the environment, which must undergo a series of biochemical transformations before it can be incorporated into cellular components. As sulfate is highly oxidized, it must undergo assimilatory sulfate reduction to...
553

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of analytical performance of Sebia Capillarys 3 Octa electrophoresis method for serum protein electrophoresis.

The Medical journal of Malaysia·2025
Same author

A frontal external ventricular drain causing a third cranial nerve palsy.

British journal of neurosurgery·2016
Same author

Some mechanical properties of a highly cross-linked, microwave-polymerized, injection-molded denture base polymer.

The International journal of prosthodontics·2001
Same author

Alteration of cell-wall composition of Fusarium oxysporum by copper stress.

Folia microbiologica·1998
Same author

The effect of filler content and processing variables on dimensional accuracy of experimental composite inlay material.

The Journal of prosthetic dentistry·1997
Same author

The optimum curing cycle for a light- and heat-cured composite inlay material.

Journal of oral rehabilitation·1997

Related Experiment Video

Updated: Apr 29, 2026

Customization of Aspergillus niger Morphology Through Addition of Talc Micro Particles
10:51

Customization of Aspergillus niger Morphology Through Addition of Talc Micro Particles

Published on: March 15, 2012

21.9K

Selenoprotein in Aspergillus terreus.

S E Ramadan1, A A Razak

  • 1Faculty of Science for Girls, Al-Azhar University, Medinet Nasr, Cairo, Egypt.

Biological Trace Element Research
|December 1, 1988
PubMed
Summary

Aspergillus terreus metabolizes selenium, incorporating it into amino acids and proteins. This fungus does not distinguish between sulfur and selenium during this process.

Area of Science:

  • Biochemistry
  • Mycology
  • Environmental Science

Background:

  • Fungi play crucial roles in biogeochemical cycles.
  • Selenium is an essential trace element with complex biological interactions.
  • Understanding selenium metabolism in fungi like Aspergillus terreus is vital.

Purpose of the Study:

  • To investigate the metabolic fate of selenite in Aspergillus terreus.
  • To identify specific seleno-amino acids and proteins formed.
  • To determine if Aspergillus terreus discriminates between selenium and sulfur.

Main Methods:

  • Culturing Aspergillus terreus with selenite.
  • Analyzing fungal biomass for selenium incorporation.
  • Using labeled selenium studies.

More Related Videos

Author Spotlight: Advancing Structural and Biochemical Studies of Proteins Through Thermal Shift Assays
03:09

Author Spotlight: Advancing Structural and Biochemical Studies of Proteins Through Thermal Shift Assays

Published on: August 9, 2024

1.5K
Saccharomyces cerevisiae Models of Alzheimer's Disease to Screen Genes, Mutations, and Chemicals Affecting Amyloid Beta Production by γ-Secretase
11:57

Saccharomyces cerevisiae Models of Alzheimer's Disease to Screen Genes, Mutations, and Chemicals Affecting Amyloid Beta Production by γ-Secretase

Published on: June 24, 2025

732

Related Experiment Videos

Last Updated: Apr 29, 2026

Customization of Aspergillus niger Morphology Through Addition of Talc Micro Particles
10:51

Customization of Aspergillus niger Morphology Through Addition of Talc Micro Particles

Published on: March 15, 2012

21.9K
Author Spotlight: Advancing Structural and Biochemical Studies of Proteins Through Thermal Shift Assays
03:09

Author Spotlight: Advancing Structural and Biochemical Studies of Proteins Through Thermal Shift Assays

Published on: August 9, 2024

1.5K
Saccharomyces cerevisiae Models of Alzheimer's Disease to Screen Genes, Mutations, and Chemicals Affecting Amyloid Beta Production by γ-Secretase
11:57

Saccharomyces cerevisiae Models of Alzheimer's Disease to Screen Genes, Mutations, and Chemicals Affecting Amyloid Beta Production by γ-Secretase

Published on: June 24, 2025

732
  • Protein hydrolysis and amino acid analysis.

    • Main Results:

    • Metabolism of selenite into selenomethionine and selenocysteine.
    • Formation of non-protein seleno-amino acids.
    • Incorporation of selenium into various proteins, mainly low molecular weight ones.
    • Evidence of fungal failure to differentiate between sulfur and selenium.

    Conclusions:

    • Aspergillus terreus incorporates selenium into both protein and non-protein compounds.
    • The fungus does not discriminate between sulfur and selenium during metabolism.
    • Findings challenge previous assumptions about selenium handling by this fungus.