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Updated: Apr 29, 2026
Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
Intraperitoneal chemotherapy in advanced epithelial ovarian cancer: a survey
Giuseppe Grosso1, Diego Rossetti, Federico Coccolini
1Department of Gynecology and Obstetrics, Papa Giovanni XXIII Hospital, Piazza OMS 1, Bergamo, Italy.
Introduction:
Intraperitoneal chemotherapy preceded by cytoreductive surgery should be the standard of care in the treatment of advanced epithelial ovarian cancer. This combination has been extensively examined in both the clinical and preclinical settings with favourable oncologic outcomes. Unfortunately, despite the existence of these evidence-based data, this management strategy remains underutilised.
Materials And Methods:
We review and discuss the role of intraperitoneal chemotherapy with particular emphasis about the pharmacokinetics and pharmacodynamics aspects, the mode of administration, the reported side effects, the compliance of the patients and the clinical ongoing studies.
Conclusions:
Further studies investigating the pharmacokinetics and pharmacodynamics aspect of IP route may help to reduce toxicity pending more effective treatments.
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