Diagnostic value of dynamic and morphologic breast MRI analysis in the diagnosis of breast cancer
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Published on: December 15, 2014
Małgorzata Stusińska1, Jadwiga Szabo-Moskal1, Barbara Bobek-Billewicz2
1Department of Diagnostic Imaging and Interventional Radiology, Oncology Center in Bydgoszcz, Bydgoszcz, Poland.
Background:
Mammography is the most widely used method of breast imaging. However, its low sensitivity poses a problem. Breast MRI is one of so the called "complementary" breast imaging methods. The purpose of this study was to improve the specificity of breast MRI by combining 2 methods: dynamic and morphologic analysis of enhancing lesions.
Material/Methods:
222 women aged 19-76 years, who underwent breast MRI examination between November 2002 and April 2004 at the Radiology Department of Oncology Center in Bydgoszcz, were included in this study.
Results:
The pathological examination revealed cancer in 55 women (25%). No cancer was found in 167 women (75%), 56 of which were verified pathologically, 111 by cytology and/or during follow-up (at least 24 months). Results of breast MRI were positive in 80 women (36%), in 54 of which cancer was found during pathological examination, 26 breast MRI results were false positive. Sensitivity and specificity of breast MRI for dynamic analysis were 87% and 72%, respectively; in case of morphologic analysis 98% and 74%, respectively. The combined dynamic and morphologic analysis achieved high (84%) specificity without loss of sensitivity (98%). The difference in specificity between the evaluated methods was statistically significant (p<0.05).
Conclusions:
The combined dynamic and morphologic breast MRI analysis is a useful method for the diagnosis of breast cancer.
