Related Experiment Video
Updated: Apr 29, 2026
08:51
Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
9.7K
[Appendiceal diverticulitis: comparative study of 7 cases versus 442 acute appendicitis]
Acta Gastroenterologica Latinoamericana
|May 23, 2014
Summary
Appendiceal diverticulitis (AD) affects older patients and presents similarly to acute appendicitis (AA). However, AD shows a higher rate of perforation, necessitating careful diagnosis.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Abdominal Imaging
Background:
- Appendiceal diverticulitis (AD) is an uncommon cause of acute appendicitis (AA).
- AD is often diagnosed post-appendectomy through pathological examination.
- Distinguishing AD from AA pre-operatively can be challenging.
Purpose of the Study:
- To compare the clinical characteristics and outcomes of appendiceal diverticulitis (AD) versus typical acute appendicitis (AA).
- To identify potential differences in patient demographics, laboratory findings, and complication rates between AD and AA.
Main Methods:
- A retrospective analytic study was conducted over 51 months (January 2009 - March 2013).
- Patients with clinical or radiological suspicion of appendicitis, confirmed intraoperatively and pathologically, were included.
- Data from 449 patients (442 AA, 7 AD) were analyzed.
Main Results:
- Appendiceal diverticulitis (AD) was more prevalent in women (57%) with a median age of 44, while acute appendicitis (AA) was more common in men (61%) with a median age of 28.
- Laboratory findings (leukocyte count, neutrophils, C-reactive protein) and diagnostic scores (Alvarado, appendicitis diagnostic score) showed similar profiles between AD and AA.
- Appendiceal perforation occurred in 43% of AD cases compared to 18% of AA cases.
Conclusions:
- Appendiceal diverticulitis (AD) typically presents in older individuals compared to acute appendicitis (AA).
- Clinical and laboratory presentations of AD are similar to AA, making pre-operative differentiation difficult.
- AD is associated with a significantly higher rate of appendiceal perforation than AA.
Related Concept Videos
01:29Appendicitis-II: Diagnostic Studies and Management
935
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
935
01:22Appendicitis-I: Introduction
4.4K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
4.4K
01:19Appendicitis
29
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
29
01:27Diverticular Disease of the Colon
35
Diverticular disease involves the formation of diverticula—small sac-like outpouchings of the colonic wall—and their complications. It most commonly affects the sigmoid colon due to higher intraluminal pressure and structural vulnerability. It results from structural weakness and increased pressure in the colon, producing pseudodiverticula that may remain silent or progress to inflammation and serious complications.Structure of DiverticulaIn diverticulosis, these outpouchings are...
35
01:26Inflammatory Bowel Disease I: Introduction
37
Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows...
37
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
842
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
842