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Myocardial performance index in patients with dipper and nondipper hypertension

Cengiz Başar1, Feyzullah Beşli, Yasin Türker

  • 1aDepartment of Cardiology, Düzce Atatürk State Hospital, Turkey Düzce State Hospital Departments of bCardiology cPathology, Düzce University Faculty of Medicine Hospital, Düzce dDepartment of Cardiology, Anatolia Hospital, Kastamonu eDepartment of Cardiology, Medeniyet University Faculty of Medicine Hospital, İstanbul, Turkey.

Blood Pressure Monitoring
|May 23, 2014
PubMed

Insights

Left ventricular myocardial performance index (MPI) is elevated in hypertensive patients with the nondipper blood pressure pattern. This suggests MPI may help diagnose left ventricular dysfunction in nondipper hypertension.

Area of Science:

  • Cardiology
  • Hypertension Research
  • Echocardiography

Background:

  • Essential hypertension affects a significant portion of the population.
  • The nondipper blood pressure pattern is associated with increased cardiovascular risk.
  • Left ventricular myocardial performance index (LV MPI) is a marker of global left ventricular function.

Purpose of the Study:

  • To investigate the relationship between LV MPI and the nondipper blood pressure pattern in hypertensive patients.
  • To determine if LV MPI can serve as a diagnostic or monitoring tool for left ventricular dysfunction in nondipper hypertension.

Main Methods:

  • Prospective study including hypertensive patients diagnosed with essential hypertension.
  • Patients categorized into dipper and nondipper groups based on ambulatory blood pressure monitoring.
  • Two-dimensional and Doppler echocardiography utilized to assess LV MPI from tissue Doppler imaging parameters.

Main Results:

  • No significant differences in antihypertensive medication use, age, BMI, lipid profiles, or smoking status between dippers and nondippers.
  • Significantly higher LV MPI values observed in the nondipper group compared to the dipper group.
  • LV MPI showed a negative correlation with the rate of nocturnal systolic and diastolic blood pressure fall.

Conclusions:

  • LV MPI is significantly disturbed in hypertensive patients exhibiting a nondipper pattern.
  • LV MPI holds potential as a diagnostic and follow-up tool for global LV dysfunction in nondipper hypertension.
  • Further prospective research is warranted to validate these findings.
Abstract

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