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Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse
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Optogenetic stimulation of DAergic VTA neurons increases aggression

Q Yu1, C M Teixeira2, D Mahadevia2

  • 11] Division of Developmental Neuroscience, Department of Psychiatry, Columbia University, New York, NY, USA [2] Department of Biological Sciences, Columbia University, New York, NY, USA.

Molecular Psychiatry
|May 23, 2014
PubMed
Summary

No abstract available in PubMed .

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Humans engage in aggression when they seek to cause harm or pain to another person. Aggression takes two forms depending on one’s motives: hostile or instrumental. Hostile aggression is motivated by feelings of anger with intent to cause pain; a fight in a bar with a stranger is an example of hostile aggression. In contrast, instrumental aggression is motivated by achieving a goal and does not necessarily involve intent to cause pain (Berkowitz, 1993); a contract killer who murders for...
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