Dural plasmacytoma mimicking meningioma
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Updated: Apr 29, 2026

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
Negar Azarpira1, Puria Noshadi, Sara Pakbaz
1Transplant Research Center, Department of Pathology, Shiraz, Iran.
Abstract:
Plasma cell tumors are characterized by a monoclonal proliferation of immunoglobulin-secreting plasma cells. Dural infiltration of plasma cells without involvement of the parenchyma, leptomeninges or skull is a rare event. We present a 34-year-old man presenting with hallucination and amnesia. Magnetic resonance imaging revealed a left fronto-temporal mass with a dural tail mimicking meningioma. The mass was excised and histopathological examination revealed sheet of mature plasma cells. The cells were immunoreactive for kappa light chain, MUM1, CD38, and negative for epithelial membrane antigen. There was no recurrence after postoperative radiotherapy. Intracranial involvement from plasmacytoma should be considered in a case of solitary dural mass.
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