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First documented case of human infection with ovine Shiga-toxin-producing Escherichia coli serotype O52:H45

Sadjia Bekal1, Danielle Ramsay, Fabien Rallu

  • 1a Laboratoire de santé publique du Québec, 20045 chemin Ste-Marie, Sainte-Anne-de-Bellevue, QC H9X 3R5, Canada.

Canadian Journal of Microbiology
|May 23, 2014
PubMed

Insights

A non-O157 Shiga-toxin-producing Escherichia coli (STEC) infection occurred in an infant. Exposure to contaminated sheep meat after Eid al-Adha was identified as the likely source, marking the first human infection case with this STEC serotype.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Food Safety

Background:

  • Shiga-toxin-producing Escherichia coli (STEC) are significant foodborne pathogens.
  • Non-O157 STEC serotypes are increasingly recognized as causes of human illness.
  • The Muslim feast of sacrifice (Eid al-Adha) involves widespread animal slaughter and meat consumption, presenting potential exposure risks.

Observation:

  • An 8-month-old child presented with symptoms of STEC infection.
  • Epidemiological investigation linked the child's illness to consumption of contaminated sheep meat.
  • The meat was acquired following the Eid al-Adha festival.

Findings:

  • Microbiological and molecular typing identified the causative agent as an ovine STEC strain, serotype O52:H45.
  • The identified strain possessed the stx1 gene but lacked eae and hlyA genes.
  • This represents the first documented human infection with the STEC O52:H45 serotype.

Implications:

  • Highlights the potential risk of non-O157 STEC transmission from livestock to humans, particularly around religious festivals.
  • Underscores the need for enhanced surveillance and food safety measures for non-O157 STEC strains.
  • Contributes to the understanding of STEC serotype diversity and their pathogenic potential in humans.
Keywords:
Escherichia coliO52:H45STEC autre que l’O157Shiga toxinmoutonnon-O157 STECsheeptoxine Shiga

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