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Updated: Apr 29, 2026
Clinical Microfluidic Chip Platform for the Isolation of Versatile Circulating Tumor Cells
Published on: October 13, 2023
A size amplified immune magnetic microbeads strategy in the rapid detection of circulating tumor cells
Hongyan Zhang1, Yanhong Wang, Qingling Li
1College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan, China. tangb@sdnu.edu.cn.
Abstract:
Using anti-EpCAM antibody modified magnetic microbeads allowed us to simultaneously apply size-amplification and magnetic labelling of CTCs to the capture and purification of CTCs by membrane filtration and immune-magnetic separation. High purity capture (>98%), rapid (<2 hours) and simple detection of CTCs were realized.
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