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Updated: Apr 29, 2026

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications
Published on: September 16, 2022
Validation of free flow electrophoresis as a novel plasma and serum processing and fractionation method in biobanking
Gwenaelle Gaillard1, Jean-Pierre Trezzi, Fotini Betsou
11 Biobanque de Picardie, Saleux, France .
Abstract:
Free flow electrophoresis (FFE) is a fractionation method, based on isoelectric focusing (IEF). We validate the reproducibility of the method and show that it can be applied by biobanks in order to fractionate fluid biospecimens efficiently and reproducibly and to facilitate downstream proteomic applications. We also propose a simple method allowing researchers to assess the reproducibility of each FFE run.
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