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Hypertensive heart disease and endocardially recorded late potentials
C Bethge1, S Recker, B E Strauer
1Department of Internal Medicine, Philipps-University Marburg, F.R.G.
Journal of Cardiovascular Pharmacology
|January 1, 1987
Summary
Ventricular late potentials and arrhythmias are primarily observed in patients with decompensated hypertensive heart disease, indicating impaired left ventricular function. These findings highlight potential risks associated with reduced cardiac pumping ability in such patients.
Area of Science:
- Cardiology
- Electrophysiology
- Cardiac Pathophysiology
Background:
- Hypertensive heart disease can lead to impaired cardiac function.
- Ventricular arrhythmias pose a significant risk in patients with heart disease.
Purpose of the Study:
- To investigate the presence of ventricular late potentials in patients with compensated and decompensated hypertensive heart disease.
- To correlate ventricular late potentials with left ventricular function and arrhythmias.
Main Methods:
- Endocardial catheter mapping was used to record ventricular late potentials.
- Twenty-four-hour Holter monitoring (ECG) was performed to detect arrhythmias.
- Left ventricular ejection fraction and cardiac index were assessed.
Main Results:
- Left ventricular late potentials were detected in 100% of decompensated patients versus 8% of compensated patients.
- Late potentials were associated with reduced left ventricular ejection fraction (<62%) and cardiac index (<=2.9 L/min/m2).
- Ventricular arrhythmias, including malignant types, were more prevalent in patients with late potentials and impaired cardiac function.
Conclusions:
- Ventricular late potentials are highly prevalent in decompensated hypertensive heart disease.
- The presence of late potentials correlates with reduced left ventricular function and increased risk of ventricular arrhythmias.
- Endocardial recording of late potentials may aid in risk stratification for hypertensive heart disease patients.