Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K
Glaucoma: Overview01:25

Glaucoma: Overview

1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

282
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
282

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Stepwise emergence of recombination suppression precedes fissiparous asexuality in the planarian Schmidtea mediterranea.

Nature communications·2026
Same author

National recommendations for the safe handling of hazardous drugs by pharmacy technicians in Portugal: A modified delphi study.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners·2026
Same author

Complexity and innovation in carnivorous plant genomes.

Trends in genetics : TIG·2026
Same author

How much can reticulate evolution entangle plant systematics? Revisiting subfamilial classification of the Malvatheca clade (Malvaceae) on the basis of phylogenomics.

Frontiers in plant science·2026
Same author

Chromosome size as a robust predictor of recombination rate: insights from holocentric and monocentric systems.

Genetics·2025
Same author

Giant mitogenomes in Rhynchospora are a result of nuclear gene and retrotransposon insertions in intergenic spaces.

Annals of botany·2025

Related Experiment Video

Updated: Apr 29, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.0K

Managing advanced unilateral pseudoexfoliative glaucoma.

André Marques1

  • 1Hospital de Egas Moniz, Lisboa, Portugal.

BMJ Case Reports
|May 23, 2014
PubMed
Summary
This summary is machine-generated.

This case study highlights laser trabeculoplasty as an effective treatment for unilateral pseudoexfoliative glaucoma, reducing intraocular pressure (IOP) and preventing progression. It offers a safer alternative to surgery, minimizing risks associated with long-term medical therapy.

More Related Videos

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.7K
Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

3.1K

Related Experiment Videos

Last Updated: Apr 29, 2026

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.0K
Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

1.7K
Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

3.1K

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Medical Case Reports

Background:

  • Glaucoma management primarily relies on reducing intraocular pressure (IOP).
  • Long-term topical IOP-lowering medications can cause significant ocular side effects.
  • Pseudoexfoliative glaucoma requires careful treatment considerations.

Observation:

  • A patient with unilateral pseudoexfoliative glaucoma presented with advanced optic neuropathy and treatment-related ocular side effects.
  • The patient had been managed for years with triple topical IOP-lowering drugs.
  • Laser trabeculoplasty was chosen over surgery due to potential risks like the 'wipe-out phenomenon'.

Findings:

  • Laser trabeculoplasty effectively reduced IOP in the patient.
  • No glaucoma progression was observed during the 1-year follow-up period.
  • The chosen intervention was well-tolerated with no new significant side effects.

Implications:

  • Laser trabeculoplasty is a viable and effective alternative to medical therapy for selected glaucoma cases.
  • Ocular side effects of long-term glaucoma medications necessitate exploring alternative treatment options.
  • Careful patient discussion regarding treatment risks and benefits is crucial for preserving visual function and quality of life.