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[Tumor resections in the liver].

M Trede1, M Raute, J Sturm

  • 1Chirurg. Klinik im Klinikum Mannheim, Universität Heidelberg.

Langenbecks Archiv Fur Chirurgie. Supplement II, Verhandlungen Der Deutschen Gesellschaft Fur Chirurgie. Deutsche Gesellschaft Fur Chirurgie. Kongress
|January 1, 1989
PubMed
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Surgical resection offers a potential cure for primary malignant liver tumors. While challenging, curative-intent surgery achieved a 17% five-year survival rate in this study, excluding hospital mortality.

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Gastroenterology

Context:

  • Primary malignant liver tumors are rare but aggressive.
  • Surgical management is complex, with many cases deemed inoperable upon presentation.
  • Long-term outcomes for resectable liver cancers require further investigation.

Purpose:

  • To evaluate the outcomes of surgical resection for primary malignant liver tumors.
  • To determine the resectability rates and survival following curative-intent surgery.
  • To analyze hospital mortality and long-term survival, including recurrence-free survival.

Summary:

  • Over 16 years, 54 patients with primary malignant liver tumors were analyzed.
  • 44 patients underwent laparotomy, with 19 found to be inoperable.

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  • 25 patients (47%) received resection with curative intent, including various hepatectomy types.
  • Hospital mortality was 8%. Median survival post-resection was 22 months.
  • Four patients survived over 5 years, with three remaining recurrence-free (17% 5-year survival rate, excluding hospital mortality).

    • Impact:

    • This study highlights the feasibility and potential long-term benefits of surgical resection for selected patients with primary malignant liver tumors.
    • It provides crucial data on resectability, surgical outcomes, and survival rates, informing clinical decision-making.
    • The findings underscore the importance of experienced surgical teams in managing these complex cases.