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Related Experiment Video

Updated: Apr 29, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Periocular hemangiomas and lymphangiomas.

Rachel E Reem¹, Richard P Golden²

¹Department of Ophthalmology, Nationwide Children's Hospital, 700 Children's Drive ED5 F2, Columbus, OH 43205, USA.

Pediatric Clinics of North America

|May 24, 2014

Summary

This summary is machine-generated.

Infantile hemangiomas and lymphangiomas are common childhood tumors. Early ophthalmologist referral is crucial for periocular lesions to prevent vision loss and other serious complications.

Keywords:

Amblyopia Orbital lymphatic malformation Percutaneous sclerotherapy Periocular hemangioma Venous-lymphatic malformation

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Area of Science:

Ophthalmology
Pediatric Oncology
Vascular Tumors

Background:

Infantile hemangiomas are the most common pediatric benign tumors.
Lymphangiomas are benign hamartomatous vascular tumors.
Periocular location of these tumors poses significant risks.

Purpose of the Study:

To highlight the importance of recognizing periocular hemangiomas and lymphangiomas.
To inform pediatricians about potential complications.
To emphasize the necessity of ophthalmologist referral.

Main Methods:

Review of clinical characteristics of periocular hemangiomas and lymphangiomas.
Discussion of potential ophthalmologic complications.
Guidance on diagnostic and management pathways.

Main Results:

Periocular hemangiomas and lymphangiomas can cause visual axis obstruction, leading to amblyopia.
Complications include proptosis, ocular motility issues, optic nerve injury, and corneal disease.
Prompt evaluation by an ophthalmologist is essential.

Conclusions:

Pediatricians must be aware of these conditions and their potential sequelae.
Referral to an ophthalmologist is mandatory for all children with periocular hemangiomas or lymphangiomas.
Timely intervention can prevent irreversible vision impairment.