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NDM-1-producing Enterobacteriaceae from South Africa: moving towards endemicity?
Joseph E Rubin1, Gisele Peirano2, Abdool K Peer3
1Division of Microbiology, Calgary Laboratory Services, University of Calgary, Calgary, Alberta, Canada; Departments of Pathology & Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Veterinary Microbiology, University of Saskatchewan, Saskatoon, SK, Canada.
Abstract:
We describe 4 patients infected with NDM-1 Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens from South Africa that co-produced SHV-12, CTX-M-3, and CTX-M-15 and were positive for qnrS, qnrA, aac(6')-Ib-cr, rmtF, rmtC, and armA. Plasmids belonged to IncN, IncA/C replicon types with ccdAB and vagC/D addiction factors. Local and imported cases of NDM-producing bacteria co-exist within South Africa.
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