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Related Concept Videos

Whole Body Regeneration01:33

Whole Body Regeneration

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Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
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Meristems and Plant Growth02:36

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Plants grow throughout their lives; this is called indeterminate growth, and it distinguishes plants from most animals. Although certain parts of plants stop growing (e.g., leaves and flowers), others grow continuously—like roots and stems.
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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
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Stem Cell Culture01:17

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
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Related Experiment Video

Updated: Apr 29, 2026

Planarian Immobilization, Partial Irradiation, and Tissue Transplantation
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Stem cells and regeneration in plants.

Giovanni Sena1

  • 1Department of Life Sciences, South Kensington Campus, Imperial College London, London, UK.

Nephron. Experimental Nephrology
|May 24, 2014
PubMed
Summary

Plant meristems exhibit developmental plasticity and tissue regeneration capabilities. However, the direct comparison of plant stem cells to animal stem cells remains debated, especially concerning root regeneration in Arabidopsis mutants.

Area of Science:

  • Plant biology
  • Developmental biology
  • Regenerative medicine

Background:

  • Plants display indeterminate post-embryonic development, including continuous shoot and root branching.
  • High tissue regeneration competence is a hallmark of plant developmental plasticity.
  • The analogy of plant meristem cells to animal stem cells is debated in plant science.

Purpose of the Study:

  • To review key observations and experimental results on plant tissue regeneration.
  • To examine stem cell activity in plants and its role in regeneration.
  • To critically evaluate the definition and utility of 'stem cell' in the context of plant development.

Main Methods:

  • Review of experimental results from plant regeneration studies.
  • Focus on the model system Arabidopsis thaliana.

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  • Analysis of recent findings on root regeneration in Arabidopsis mutants.

    • Main Results:

    • Plants possess remarkable somatic developmental plasticity enabling regeneration.
    • Stem cell-like activity in plant meristems is crucial for development and regeneration.
    • Recent experiments challenge the direct application of animal stem cell concepts to plants.

    Conclusions:

    • The concept of stem cells, imported from animal literature, aids in describing plant development but its utility is questioned.
    • Defining 'stem cell-ness' in plants, particularly for tissue regeneration, requires careful consideration of experimental evidence.
    • Further research, especially on mutants like those in Arabidopsis, is needed to clarify the role and definition of plant stem cells.