Characterizing weekly self-reported antihypertensive medication nonadherence across repeated occasions
Corrine I Voils1, Heather A King2, Brian Neelon1
1Health Services Research and Development, Durham Veterans Affairs Medical Center, NC, USA ; Department of Medicine, Duke University, NC, USA.
Patient Preference and Adherence
|May 24, 2014
Summary
Medication nonadherence varies weekly, with forgetting, being busy, and traveling as key reasons. Both individual differences and daily fluctuations contribute equally to this nonadherence in patients.
Area of Science:
- Pharmacology
- Patient Adherence Research
- Health Services Research
Background:
- Weekly variability in medication nonadherence, both between and within individuals, remains poorly understood.
- Understanding adherence patterns is crucial for effective chronic disease management.
Purpose of the Study:
- To characterize medication nonadherence patterns across repeated, closely spaced assessment occasions.
- To identify common reasons for medication nonadherence in adult outpatients.
Main Methods:
- Prospective cohort study with four unannounced telephone assessments, approximately two weeks apart.
- Adult outpatients on antihypertensive medication reported on the extent and reasons for nonadherence during each assessment.
Main Results:
- Nonadherence was reported in 17.5% of occasions by 36% of participants.
- Forgetting (39.5%), being busy (23.7%), and traveling (19.7%) were the primary reasons for nonadherence.
- Within-person fluctuations and between-person differences each accounted for 50% of the variability in nonadherence extent.
Conclusions:
- Interventions targeting medication nonadherence should consider both the variability in adherence levels and the specific reasons cited by patients.
- Tailoring interventions based on individual adherence patterns and common barriers like forgetting or being busy is recommended.
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