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Updated: Apr 29, 2026

Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo
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EPIQ Review.

C David Simpson, Judith Hawes, Andrew G James

    Paediatrics & Child Health
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    Summary
    This summary is machine-generated.

    Implementing care bundles with checklists during central-line insertions significantly reduces catheter-related bloodstream infections in intensive care units. This evidence supports their use for preventing nosocomial infections.

    Keywords:
    Catheter-related infectionsCathetersChecklistHealth careIndwelling/adverse eventsInfection control/methodsIntensive care unitsQuality assurance

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    Area of Science:

    • Infectious Disease Epidemiology
    • Critical Care Medicine
    • Healthcare Quality Improvement

    Background:

    • Nosocomial infections are a significant concern in intensive care units (ICUs).
    • Aseptic technique during line insertion is crucial for preventing infections.
    • Care bundles incorporating checklists are used to improve compliance and reduce infections.

    Purpose of the Study:

    • To evaluate the effectiveness of bundled interventions, including checklists, in reducing central-line-associated bloodstream infections (CLABSIs).
    • To assess the impact of these interventions in ICU patient populations.

    Main Methods:

    • A comprehensive literature review was conducted.
    • Methodology was adapted from the American Heart Association's International Liaison Committee on Resuscitation guidelines.
    • Seventeen cohort studies were included in the analysis.

    Main Results:

    • Thirteen of the seventeen cohort studies supported the intervention's effectiveness.
    • Four studies yielded neutral results.
    • Infection rates decreased from 1.6-10.8 per 1000 central-line days in control groups to 0.0-3.8 per 1000 central-line days in intervention groups.

    Conclusions:

    • There is fair evidence supporting the use of care bundles with checklists for central-line insertion in ICUs.
    • These interventions are effective in reducing the incidence of catheter-related bloodstream infections.
    • The findings advocate for the widespread adoption of these bundles to enhance patient safety.