Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

2.4K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.4K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

3.8K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
3.8K
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

1.6K
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
1.6K
Stem Cell Culture01:17

Stem Cell Culture

4.5K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
4.5K
Renewal of Skin Epidermal Stem Cells01:12

Renewal of Skin Epidermal Stem Cells

2.4K
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
2.4K
iPS Cell Differentiation01:22

iPS Cell Differentiation

2.2K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Introduction to Generative Artificial Intelligence: Contextualizing the Future.

Archives of pathology & laboratory medicine·2024
Same author

Effect of Barley on Postprandial Blood Glucose Response and Appetite in Healthy Individuals: A Randomized, Double-Blind, Placebo-Controlled Trial.

Nutrients·2024
Same author

Oxygen-Doped 2D In<sub>2</sub>Se<sub>3</sub> Nanosheets with Extended In-Plane Lattice Strain for Highly Efficient Piezoelectric Energy Harvesting.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2024
Same author

Correlation between inflammatory markers and enhanced recovery after surgery (ERAS) failure in laparoscopic colectomy.

Surgery today·2024
Same author

Case report: Peritonitis caused by Pantoea agglomerans from pet dog exposure in peritoneal dialysis.

Medicine·2024
Same author

Histopathologic findings of the lens capsule and persistent hyperplastic primary vitreous in Korean pediatric cataract patients.

Scientific reports·2024

Related Experiment Video

Updated: Apr 29, 2026

Creation and Transplantation of an Adipose-derived Stem Cell ASC Sheet in a Diabetic Wound-healing Model
08:06

Creation and Transplantation of an Adipose-derived Stem Cell ASC Sheet in a Diabetic Wound-healing Model

Published on: August 4, 2017

10.8K

Stem cell therapy for dermal wound healing.

Ji Yeon Kim1, Wonhee Suh1

  • 1Department of Biomedical Science, College of Life Science, CHA University, Pochon, Korea.

International Journal of Stem Cells
|May 24, 2014
PubMed
Summary
This summary is machine-generated.

Cellular therapies using adult stem cells show promise for treating chronic dermal wounds. These cells, including mesenchymal stem cells, aid healing through proliferation and growth factor production.

Keywords:
Stem cellTransplantationWound healing

More Related Videos

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
04:09

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers

Published on: March 3, 2023

4.4K
Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells
09:54

Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells

Published on: April 18, 2019

13.1K

Related Experiment Videos

Last Updated: Apr 29, 2026

Creation and Transplantation of an Adipose-derived Stem Cell ASC Sheet in a Diabetic Wound-healing Model
08:06

Creation and Transplantation of an Adipose-derived Stem Cell ASC Sheet in a Diabetic Wound-healing Model

Published on: August 4, 2017

10.8K
Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
04:09

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers

Published on: March 3, 2023

4.4K
Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells
09:54

Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells

Published on: April 18, 2019

13.1K

Area of Science:

  • Regenerative Medicine
  • Wound Healing Biology
  • Stem Cell Therapy

Background:

  • Cellular therapy is a growing field for dermal wound treatment.
  • Multipotent adult stem cells offer therapeutic advantages due to their regenerative capabilities.

Purpose of the Study:

  • To review the role of adult stem cells in dermal wound healing.
  • To explore the therapeutic potential of stem cells for chronic wound treatment, particularly in diabetic patients.

Main Methods:

  • Literature review focusing on adult stem cells.
  • Analysis of stem cell types: endothelial progenitor cells, bone marrow-derived mesenchymal stem cells, and adipose-derived mesenchymal stem cells.
  • Examination of stem cells' functions in wound healing.

Main Results:

  • Adult stem cells possess high proliferative potential.
  • Stem cells differentiate into various cell types.
  • Stem cells secrete cytokines and growth factors crucial for healing.

Conclusions:

  • Adult stem cells, especially mesenchymal stem cells, are promising for chronic wound management.
  • Further research into stem cell therapy could address significant clinical challenges in wound care.