Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Treatment Resistant Cancers

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Treatment Resistent Cancers

Treatment Resistent Cancers

Cancer Therapies

Cancer Therapies

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Integrin β<sub>3</sub> directly inhibits the Gα<sub>13</sub>-p115RhoGEF interaction to regulate G protein signaling and platelet exocytosis.

Nature communications·2023

Same author

Acupuncture improves certain aspects of sleep in hematopoietic stem cell transplantation patients: a secondary analysis of a randomized controlled trial.

Acupuncture in medicine : journal of the British Medical Acupuncture Society·2023

Same author

Integrating herbal medicine into oncology care delivery: development, implementation, and evaluation of a novel program.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer·2023

Same author

Acupuncture versus massage for pain in patients living with advanced cancer: a protocol for the IMPACT randomised clinical trial.

BMJ open·2022

Same author

Effects of Vigorous Versus Restorative Yoga Practice on Objective Cognition Functions in Sedentary Breast and Ovarian Cancer Survivors: A Randomized Controlled Pilot Trial.

Integrative cancer therapies·2022

Same author

Acupuncture in hematologic malignancies and hematopoietic cell transplantation.

Blood reviews·2022

Search research articles

Related Experiment Video

Updated: Apr 29, 2026

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

Integrative oncology: an overview.

Gary Deng¹, Barrie Cassileth¹

¹From the Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, New York, NY.

American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting

|May 27, 2014

Summary

This summary is machine-generated.

Integrative oncology uses evidence-based complementary therapies to manage cancer symptoms and improve quality of life. These nonpharmacologic approaches are distinct from unproven alternative therapies, enhancing patient well-being alongside conventional cancer care.

More Related Videos

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Published on: April 30, 2021

Related Experiment Videos

Last Updated: Apr 29, 2026

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Author Spotlight: Integrating Computational and Experimental Approaches in Precision Oncology

Published on: December 1, 2023

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

Published on: April 30, 2021

Area of Science:

Integrative Medicine
Oncology
Evidence-Based Practice

Background:

Integrative oncology focuses on symptom management using nonpharmacologic therapies.
Complementary therapies are evidence-based adjuncts to mainstream cancer care.
Alternative therapies lack scientific evidence and may be fraudulent.

Purpose of the Study:

To explore the context of integrative oncology and alternative therapies.
To review patient questions and research findings.
To guide patients and families through complex treatment decisions.

Main Methods:

Literature review of integrative and alternative therapies in oncology.
Analysis of patient-reported outcomes and physician recommendations.
Exploration of the medical and sociocultural context.

Main Results:

Complementary therapies demonstrate safety, value, and benefits in managing physical and emotional symptoms.
Alternative therapies lack scientific validation and can be harmful.
Integrative oncology enhances patient quality of life and the physician-patient relationship.

Conclusions:

Integrative oncology, utilizing complementary therapies, is a rational and beneficial approach to cancer care.
Distinguishing between complementary and alternative therapies is crucial for patient safety.
Nonpharmacologic modalities improve symptom burden and patient well-being.