Related Experiment Video
Updated: Apr 29, 2026

07:57
A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
21.6K
Avoidance mediates the relationship between anxiety and depression over a decade later
Nicholas C Jacobson1, Michelle G Newman1
1The Pennsylvania State University, United States.
Journal of Anxiety Disorders
|May 27, 2014
Summary
Early anxiety predicts later depression in adolescents, with avoidance behaviors partially explaining this link. Experiencing trauma did not alter the relationship between avoidance and depression.
Area of Science:
- Psychology
- Psychiatry
- Longitudinal Studies
Background:
- Anxiety and depression are frequently comorbid conditions.
- Understanding the longitudinal pathways between anxiety and depression is crucial for effective interventions.
Purpose of the Study:
- To investigate the longitudinal relationship between adolescent anxiety and later depression.
- To examine the mediating role of avoidance behaviors.
- To explore the moderating effect of trauma on this relationship.
Main Methods:
- Longitudinal study with N=6504 adolescents.
- Baseline measures of anxiety and depression.
- Follow-up measures of avoidance (1 year), trauma (6-8 years), and depression (12-14 years).
- Structural equation modeling analysis.
Main Results:
- Adolescent anxiety significantly predicted depression over 12-14 years later.
- Avoidance behaviors partially mediated the relationship between earlier anxiety and later depression.
- Trauma did not moderate the association between avoidance and depression.
Conclusions:
- Anxiety may contribute to the development of depression in adolescents through avoidance.
- The pathway from anxiety to depression via avoidance appears robust, irrespective of trauma exposure.
Related Concept Videos
Self-Discrepancy and Its Effects
512
Self-discrepancy theory explains how people compare their actual self to their ideal and ought selves and how mismatches between these self-guides can lead to emotional distress. Developed by E. Tory Higgins, the theory distinguishes among three components of self-concept: the actual self, the ideal self, and the ought self. These refer respectively to how individuals perceive themselves, how they aspire to be, and how they believe they are obligated to be. Emotional well-being, self-esteem,...
512
Theory of Romantic Attachment in Adulthood
40.3K
Attachment is a long-standing connection or bond with others. While Attachment Theory was conceived in developmental psychology to describe infant-caregiver bonding, it's been extended into adulthood to include romantic relationships.
40.3K
Self-Discrepancy Theory
17.9K
One influential perspective on what motivates people's behavior is detailed in Tory Higgin's self-discrepancy theory (Higgins, 1987). He proposed that people hold disagreeing internal representations of themselves that lead to different emotional states.
17.9K
Anxiety: Overview
1.3K
Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
1.3K
Stress and Mental Health
1.7K
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
Individuals with depression often experience challenges in both their personal and professional...
1.7K
Social Anxiety Disorder
847
Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
847

