Do certain drugs cause the megacystis-microcolon-intestinal hypoperistalsis syndrome

A case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) in the offspring of a mother who had ingested scopolamine, trimethoprim-sulfadiazine and dipyrone during pregnancy is presented. In order to determine whether a relationship exists between maternal drug ingestion and MMIHS, the need for further experimental studies is stressed.