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Updated: Apr 29, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
[Outcomes after surgery for refractory constipation patients complicated with megacolon]
Weiwei Ding1, Jun Jiang, Xiaobo Feng
1Research Institute of General Surgery, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China. jiangjun6987@163.com.
Surgical interventions effectively treat refractory constipation with megacolon, showing a 100% success rate. Procedures significantly improved patient outcomes and reduced constipation scores post-surgery.
Area of Science:
- Gastroenterology
- Colorectal Surgery
Context:
- Refractory constipation with megacolon presents a significant clinical challenge.
- Surgical options are often considered for severe, intractable cases.
Purpose:
- To evaluate the efficacy of different surgical procedures for refractory constipation complicated with megacolon.
- To analyze surgical outcomes and complications in a cohort of 112 patients.
Summary:
- Retrospective analysis of 112 patients undergoing subtotal colectomy (Jinling procedure) or total colectomy with various ileal anastomosis techniques.
- All procedures demonstrated a 100% success rate with no surgical mortality.
- Postoperative complications included diarrhea, anal pain, urinary retention, bleeding, leakage, and obstruction, with significant improvement in Wexner constipation scores and malnutrition at 6 months.
Impact:
- Surgical intervention is a highly effective treatment for refractory constipation and megacolon.
- Understanding complication profiles aids in patient selection and postoperative management.
- Improved quality of life and nutritional status observed post-surgery.
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