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Updated: Apr 29, 2026

Monitoring Spatial Segregation in Surface Colonizing Microbial Populations
Published on: October 29, 2016
Surface-associated microbes continue to surprise us in their sophisticated strategies for assembling biofilm
Daniel J Wozniak1, Matthew R Parsek2
1Department of Microbial Infection and Immunity, Department of Microbiology, Center for Microbial Interface Biology, The Ohio State University 460 W 12th Avenue, Columbus, OH 43210 USA.
Abstract:
Microorganisms are rarely found in isolation. Frequently, they live as complex consortia or communities known as biofilms. The microbes within these complex structures are typically enmeshed in a matrix of macromolecules collectively known as the extracellular polymeric substances (EPS). The last decade has seen enormous growth in the breadth and depth of biofilm-related research. An important area of focus has been the study of pure culture biofilms of different model species. This work has informed us about the different genetic determinants involved in biofilm formation and the environmental conditions that influence the process. These studies have also highlighted both species-specific aspects of biofilm development and common trends observed across many different organisms. This report highlights some exciting findings in recent biofilm-related research.
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