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Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits. Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...

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Related Experiment Video

Updated: Apr 29, 2026

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Establishment of a Human Multiple Myeloma Xenograft Model in the Chicken to Study Tumor Growth, Invasion and Angiogenesis

Published on: May 1, 2015

Aggressive angiomyxoma.

L Padmavathy¹, L Lakshmana Rao², M Dhana Lakshmi²

¹Urban Health Center, Division of Community Medicine, RMMC, Annamalai University, Annamalai Nagar, Chidambaram, Tamil Nadu, India.

Indian Dermatology Online Journal

|May 27, 2014

Summary

This summary is machine-generated.

Aggressive angiomyxoma is a rare, infiltrative tumor with abundant myxoid matrix. This report details a unique case of vaginal aggressive angiomyxoma in a 55-year-old woman, highlighting its rarity.

Area of Science:

Oncology
Pathology
Gynecologic Oncology

Background:

Myxoid tumors are defined by abundant extracellular myxoid matrix.
Aggressive tumors exhibit infiltrative growth and high recurrence rates.

Keywords:

Aggressive Carney complex angio myxoma

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