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The oxidation of an organic compound in the presence of air or oxygen is called autoxidation. For example, cumene reacts with oxygen to form hydroperoxide. Autoxidation involves initiation, propagation, and termination steps. Many organic compounds are susceptible to autoxidation—especially ethers in the presence of oxygen, which form hydroperoxides. Even though this reaction is slow, old ether bottles contain small amounts of peroxide, which leads to laboratory explosions during ether...
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Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
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Antioxidants in dermatology.

Varadraj V Pai1, Pankaj Shukla1, Naveen Narayanshetty Kikkeri2

  • 1Department of Dermatology, Goa Medical College, Goa, India.

Indian Dermatology Online Journal
|May 27, 2014
PubMed
Summary

Antioxidants combat free radicals from environmental damage, protecting cells. This discussion focuses on oxidative stress in skin and the benefits of antioxidants in dermatology.

Keywords:
Antioxidantsfree radicalsoxidative stress

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Area of Science:

  • Dermatology
  • Biochemistry
  • Environmental Health

Background:

  • Oxidative stress, caused by environmental factors like UV radiation and pollutants, contributes to cellular damage.
  • Oxidative stress and antioxidant roles are implicated in systemic diseases including obesity, atherosclerosis, and Alzheimer's disease.

Purpose of the Study:

  • To explore the specific effects of oxidative stress on skin health.
  • To elucidate the function and importance of antioxidants in dermatological applications.

Main Methods:

  • Literature review and synthesis of existing research on oxidative stress and antioxidants in dermatology.
  • Analysis of scientific data linking environmental insults to skin aging and disease.

Main Results:

  • Environmental insults generate free radicals, leading to oxidative stress and skin damage.
  • Antioxidants play a crucial role in mitigating this damage and maintaining skin health.

Conclusions:

  • Understanding oxidative stress mechanisms is key to developing effective dermatological treatments.
  • Antioxidants are vital for preventing and managing skin conditions associated with oxidative damage.