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Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Two-step synthesis of multi-substituted amines by using an N-methoxy group as a reactivity control element

Makoto Yoritate1, Tatsuhiko Meguro, Naoya Matsuo

  • 1Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1, Hiyoshi, Kohoku-ku, Yokohama 223-8522 (Japan), Fax: (+81) 45-566-1551.

Chemistry (Weinheim an Der Bergstrasse, Germany)
|May 28, 2014
PubMed

Keywords:
amidesnitrogennucleophilic additionpiperidinereactivity control

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