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Clinical characteristics and mortality risk prediction in critically ill children in Malaysian Borneo
Indra Ganesan1, Terrence Thomas, Fon En Ng
1Nephrology Service, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899. Indra.Ganesan@kkh.com.sg.
Insights
The Pediatric Index of Mortality 2 (PIM2) score effectively predicts mortality risk in a Malaysian paediatric intensive care unit (PICU). Infants under two with comorbidities faced significantly higher mortality risks.
Area of Science:
- Pediatric Intensive Care
- Clinical Epidemiology
- Healthcare Quality Benchmarking
Background:
- Mortality risk prediction scores are crucial for assessing quality of care in pediatric intensive care units (PICUs).
- Benchmarking PICU outcomes against established scores like the Pediatric Index of Mortality 2 (PIM2) is essential for quality improvement.
- Understanding demographic and diagnostic differences between patient populations (e.g., Malaysian vs. immigrant children) can inform targeted interventions.
Purpose of the Study:
- To benchmark PICU outcomes at Sabah Women's and Children's Hospital using the PIM2 score.
- To evaluate differences in admission diagnoses and patient outcomes between Malaysian and immigrant children.
- To assess the applicability of the PIM2 score in a Malaysian PICU setting.
Main Methods:
- Prospective collection of demographic and clinical data from pediatric medical patients admitted to the PICU.
- Calculation of the PIM2 risk score for mortality for all eligible patients.
- Analysis of patient demographics, admission diagnoses, and mortality, comparing Malaysian and non-Malaysian children.
Main Results:
- The study included 115 patients, with a mean age of 2.6 years; 79% were under five.
- Respiratory disorders were the leading diagnosis on admission (37%).
- Infants under two years old with comorbidities showed a significantly higher mortality risk (SMR 2.61).
Conclusions:
- The patient profile in this Malaysian PICU is comparable to other Asian PICUs.
- The PIM2 score demonstrates utility as a mortality risk prediction model for this specific population.
- While overall benchmarking showed no significant deviation, specific subgroups like young infants with comorbidities require focused attention.
Introduction:
Mortality risk prediction scores are important for benchmarking quality of care in paediatric intensive care units (PICUs). We aimed to benchmark PICU outcomes at our hospital against the Pediatric Index of Mortality 2 (PIM2) mortality risk prediction score, and evaluate differences in diagnosis on admission and outcomes between Malaysian and immigrant children.
Methods:
We prospectively collected demographic and clinical data on paediatric medical patients admitted to the PICU of Sabah Women's and Children's Hospital in Kota Kinabalu, Sabah, Malaysia. The PIM2 risk score for mortality was tabulated.
Results:
Of the 131 patients who met the inclusion criteria, data was available for 115 patients. The mean age of the patients was 2.6 ± 3.8 years, with 79% of the cohort aged less than five years. Patients were mainly of Kadazan (38%) and Bajau (30%) descent, and 26% of patients were non-citizens. Leading diagnoses on admission were respiratory (37%), neurological (18%) and infectious (17%) disorders. Out of the 29 patients who died, 23 (79%) were Malaysians and the main mortality diagnostic categories were respiratory disorder (22%), septicaemia (22%), haemato-oncological disease (17%) and neurological disorder (13%). Calculated standardised mortality ratios (SMRs) were not significantly > 1 for any patient category for variables such as age and admission diagnosis. However, infants less than two years old with comorbidities were significantly worse (SMR 2.61, 95% confidence interval 1.02-6.66).
Conclusion:
The patient profile at our centre was similar to that reported from other PICUs in Asia. The PIM2 score is a useful mortality risk prediction model for our population.
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