Clinical characteristics and mortality risk prediction in critically ill children in Malaysian Borneo

Indra Ganesan1, Terrence Thomas, Fon En Ng

  • 1Nephrology Service, KK Women's and Children's Hospital, 100 Bukit Timah Road, Singapore 229899. Indra.Ganesan@kkh.com.sg.

Insights

The Pediatric Index of Mortality 2 (PIM2) score effectively predicts mortality risk in a Malaysian paediatric intensive care unit (PICU). Infants under two with comorbidities faced significantly higher mortality risks.

Area of Science:

  • Pediatric Intensive Care
  • Clinical Epidemiology
  • Healthcare Quality Benchmarking

Background:

  • Mortality risk prediction scores are crucial for assessing quality of care in pediatric intensive care units (PICUs).
  • Benchmarking PICU outcomes against established scores like the Pediatric Index of Mortality 2 (PIM2) is essential for quality improvement.
  • Understanding demographic and diagnostic differences between patient populations (e.g., Malaysian vs. immigrant children) can inform targeted interventions.

Purpose of the Study:

  • To benchmark PICU outcomes at Sabah Women's and Children's Hospital using the PIM2 score.
  • To evaluate differences in admission diagnoses and patient outcomes between Malaysian and immigrant children.
  • To assess the applicability of the PIM2 score in a Malaysian PICU setting.

Main Methods:

  • Prospective collection of demographic and clinical data from pediatric medical patients admitted to the PICU.
  • Calculation of the PIM2 risk score for mortality for all eligible patients.
  • Analysis of patient demographics, admission diagnoses, and mortality, comparing Malaysian and non-Malaysian children.

Main Results:

  • The study included 115 patients, with a mean age of 2.6 years; 79% were under five.
  • Respiratory disorders were the leading diagnosis on admission (37%).
  • Infants under two years old with comorbidities showed a significantly higher mortality risk (SMR 2.61).

Conclusions:

  • The patient profile in this Malaysian PICU is comparable to other Asian PICUs.
  • The PIM2 score demonstrates utility as a mortality risk prediction model for this specific population.
  • While overall benchmarking showed no significant deviation, specific subgroups like young infants with comorbidities require focused attention.
Abstract

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