MOSAIC_SSD: a new web tool for species sensitivity distribution to include censored data by maximum likelihood
Guillaume Kon Kam King1, Philippe Veber, Sandrine Charles
1UMR CNRS 5558-Laboratoire de Biométrie et Biologie Évolutive, Unviersite Claude Bernard, Lyon, Villeurbanne, France.
This study introduces a method to include censored data in species sensitivity distribution (SSD) analysis, improving ecological risk assessment. The MOSAIC_SSD tool enhances data representativeness and prediction accuracy for hazardous concentrations.
Area of Science:
- Environmental toxicology
- Ecotoxicology
- Ecological risk assessment
Background:
- Censored data are prevalent in species sensitivity distribution (SSD) analyses but often excluded, leading to reduced dataset size and representativeness.
- Excluding censored data can result in less reliable ecological risk assessments and predictions of hazardous concentrations.
Purpose of the Study:
- To develop and present a method for incorporating censored data into SSD analyses.
- To introduce the MOSAIC_SSD web tool for fitting SSDs with censored and uncensored data.
- To demonstrate the added value of including censored data for improved hazardous concentration predictions.
Main Methods:
- Utilized an extension of the standard maximum likelihood method to accommodate censored data in SSD.
- Employed the R-package fitdistrplus for fitting parametric probability distributions to ecological data.
- Developed the MOSAIC_SSD web tool for comprehensive SSD analysis, including censored data handling.
Main Results:
- The MOSAIC_SSD tool successfully fits SSDs to datasets containing both censored and uncensored data.
- The tool provides predictions of hazardous concentrations with associated bootstrap confidence intervals.
- Including censored data in SSD analysis demonstrably enhances the representativeness and accuracy of predictions.
Conclusions:
- Integrating censored data into SSD analysis is feasible and significantly improves risk assessment outcomes.
- The MOSAIC_SSD web tool offers a practical solution for utilizing all available data in SSD.
- This approach leads to more robust and reliable predictions of environmental hazard concentrations.
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