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Cardiovascular implantable electronic devices in hemodialysis patients: prevalence and implications for arteriovenous
Theodore F Saad1, Waqas Ahmed, Karen Davis
1Nephrology Associates, PA, Vascular Access Center, Newark, DE; Section of Renal & Hypertensive Diseases, Department of Medicine, Christiana Care Health System, Newark, DE.
Insights
Cardiovascular implantable electronic devices (CIEDs) are common in hemodialysis patients. Ipsilateral CIEDs and arteriovenous access increase central venous interventions but do not significantly alter overall access circuit intervention rates.
Area of Science:
- Nephrology
- Cardiology
- Vascular Surgery
Background:
- Cardiovascular implantable electronic devices (CIEDs) are frequently used in patients undergoing chronic hemodialysis.
- CIED leads, often placed via the subclavian vein, can lead to venous stenosis and hypertension, complicating vascular access management.
Purpose of the Study:
- To investigate the prevalence of CIEDs in hemodialysis patients.
- To evaluate the impact of CIEDs, specifically implantable cardioverter-defibrillators (ICDs) and pacemakers, on the rates of interventions in hemodialysis access circuits and central veins.
- To compare intervention rates based on the laterality of CIED and arteriovenous access.
Main Methods:
- A retrospective review of 1235 chronic hemodialysis patients was conducted.
- Data collected included CIED presence, type (ICD or pacemaker), and hemodialysis access type.
- Intervention rates for access circuits and central veins were analyzed based on CIED and access laterality (ipsilateral vs. contralateral).
Main Results:
- CIEDs were present in 10.5% of patients (75 ICDs, 54 pacemakers).
- Overall access circuit intervention rates were similar between ipsilateral (1.53/AY) and contralateral (1.44/AY) CIED and arteriovenous access.
- Central venous intervention rates were significantly higher in the ipsilateral group (0.59/AY) compared to the contralateral group (0.28/AY) (p < 0.001).
Conclusions:
- CIEDs are highly prevalent in hemodialysis patients.
- Ipsilateral CIED and arteriovenous access leads to increased central venous interventions compared to contralateral placement.
- While central venous interventions are more frequent, overall access circuit intervention rates remain comparable, suggesting careful monitoring is needed for ipsilateral cases.
Abstract:
Cardiovascular implantable electronic devices (CIEDs) are frequently utilized in hemodialysis patients. CIED leads are typically implanted via the subclavian vein resulting in stenosis and venous hypertension. We studied 1235 chronic hemodialysis patients under the care of our nephrology practice. For each, we determined the presence of a CIED, indication for implantable cardioverter-defibrillator (ICD), and type of hemodialysis access. Records were reviewed to identify all interventions performed on the access circuit and the central veins specifically. A CIED was present in 129 patients (10.5%), including ICDs in 75 (6.1%) and pacemakers in 54 (4.4%). The access circuit intervention rate was 1.48/access year (AY) and was similar when a CIED was ipsilateral (1.53/AY) or contralateral (1.44/AY) to arteriovenous access (p = 0.477). The rate of central venous interventions was greater in the ipsilateral (0.59/AY) versus contralateral group (0.28/AY), (p < 0.001). Fifty-four of 59 patients with ipsilateral access and CIED required <2 interventions per AY, but six failed angioplasty and required access ligation. None had superior vena cava stenosis requiring intervention. We conclude that there is a high prevalence of CIEDs in our HD patients. Ipsilateral CIED and arteriovenous access results in higher central venous intervention rates compared with contralateral cases; overall access circuit intervention rates are similar.
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