Related Experiment Video
Updated: Apr 29, 2026
A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
[Difference in nitrous oxide-mediated increases in intracuff pressure between two tracheal tubes in a simulated
Background:
The purpose of this study was to compare the nitrous oxide-mediated increases in cuff pressure between a tracheal tube with a tapered cuff (Taper) or conventional high volume low pressure cuff (HVLP) utilizing a simulated pediatric lung model.
Methods:
The automated cuff pressures were adjusted to 10, 20, and 30 cmH2O. The Taper and HVLP were exposed to 80% nitrous oxide and cuff pressure was measured 15 and 30 minutes later.
Results:
The cuff pressure of the Taper was significantly lower than that of the HVLP after 15 and 30 minutes, regardless of the initial pressure.
Conclusions:
These findings suggest that the Taper may be more effective than the HVLP in preventing hyperinflation of the tracheal tube cuff in response to nitrous oxide exposure in children.
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